AI-Guided Materials Discovery: Rigaku’s Role in the Genesis Mission

"The Genesis Mission, enacted on November 24, 2025, represents a major initiative to reinvigorate fundamental scientific research in the United States. As announced at Superconducting Asia 2026 in Osaka, Japan has formally joined the Mission, underscoring its global scope and strategic importance. The Genesis Mission seeks to leverage generative and agentic artificial intelligence to transform scientific research and accelerate materials discovery across several critical technology domains.
A central requirement for AI-driven materials discovery is the availability of high-quality, real-time experimental data. In situ and inline structural characterization are therefore essential, with X-ray–based techniques serving as key enablers due to their versatility, sensitivity, and compatibility with automated workflows. To meet the growing demands of research teams supported by the Genesis Mission, Rigaku has been developing advanced automation solutions that integrate open Python-based APIs with robotic sample handling and measurement control.
In this presentation, I will discuss the most critical system-level design considerations for enabling scalable, AI-guided materials discovery, and outline how Rigaku’s instrumentation and automation platforms are being developed to support the objectives of the Genesis Mission."