PFAS Analysis 2026: Innovations in Compound Identification and Quantification

The first publications on the occurrence of PFAS, primarily PFOA and PFOS, in water emerged in the early 2000s. Over the past two decades, both our understanding of PFAS and advancements in analytical instrumentation have grown significantly. At the same time, priorities and requirements from stakeholders involved in PFAS management have evolved. Today, researchers are focused on characterizing the PFAS chemical space using non-targeted analysis, using LC- and GC-based workflows. In contrast, routine testing laboratories face increasing demand for rapid, reliable, and cost-effective workflows to deliver results quickly and efficiently for specific, although always growing, list of targets. In this presentation, we will provide an overview of the latest LC-MS/MS technologies for PFAS analysis, demonstrate their performance in advancing routine PFAS testing, and share examples of how complementary analytical workflows contribute to expanding our understanding of the PFAS chemical space.