Refresh your ex vivo tests : follow tissue tension with high resolution imaging
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Changes in skin morphology and physiology are the first observation of ageing process. A loss of firmness and elasticity is described as a main modification of skin along ages.
To screening various active ingredients or formulated products in an ex-vivo way, BioMeca® suggests to study tissue tension with confocal microscopy by analysing fluorescent beads movements after topical application of product.
Fluorescent beads are dispersed on skin surface at the same time of active ingredient or product. Then, confocal microscopy can image a large plan of skin and follow beads displacement over time.
By studying beads position over time, we can determine the capacity of product’s contractibility, and the time necessary to obtain an effect.
This method is ideal to study an effective tension effect on skin, with a visual effect and a quantitative result according applications times.
