045IC - Microhematuria to Intractable Hemorrhagic Cystitis - A Case-Based Approach to the Comprehensive Management of Urinary Tract Bleeding

Course Description:Hematuria represents one of the most common indications for urologic evaluation, and is recognized as a sign of potentially important illness. Therefore, knowledge of the differential diagnosis, principles of evaluation, and strategies for management of hematuria is critical. This course is designed to use a case-oriented format to provide a guidelines-based approach to the evaluation and management of hematuria. The target audience includes practicing urologists, advanced practice providers, as well as residents and fellows. Specifically, in attending the course, participants will obtain an in-depth understanding of the newly updated AUA Guideline recommendations for the initial evaluation of patients with asymptomatic microscopic hematuria, as well as the evidence supporting these recommendations. The new inclusion of urine tumor markers for the evaluation of select patients will be highlighted. Other national and organizational guidelines will be reviewed as well, and disparate health system implications including cost and efficiency of delivery will be discussed. Recommendations for follow-up of these patients, as well as future opportunities for further refining the approach to microhematuria evaluation, will also be covered. In addition, the course will include a discussion of the management of frequently encountered clinical challenges in renal and upper tract bleeding, as well as persistent benign prostatic hyperplasia-related bleeding. Detailed information will be provided regarding a stepwise approach to the management of patients with hemorrhagic cystitis, including intravesical treatment regimens and associated side effect profiles. Additionally, data will be reviewed supporting treatments for refractory hemorrhagic cystitis, including hyperbaric oxygen and urinary diversion.

Learning Objective 1: Implement 2025 AUA Guideline recommendations for evaluation of microscopic hematuria into clinical practice

Learning Objective 2: Recognize and develop an approach to managing upper urinary tract and prostatic-origin bleeding

Learning Objective 3: Create strategies for treating refractory hemorrhagic cystitis

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