040IC - Contemporary Management of Advanced Prostate Cancer: Guidelines and Beyond

Course Description: This course will be comprehensive AUA/SUO and NCCN Guidelines on APC in the management and outcomes of men with advanced, metastatic and CRPC. The course will include risk stratification, germline testing, PSMA PET imaging, the use of ADT in combination with novel androgen axis therapy and chemotherapy in men with newly diagnosed mHSPC. Early treatment intensification and evidenced based guidelines will be covered. This includes management of biochemical recurrence as well as metastatic disease. The course will also cover non-metastatic CRPC, and treatment for mCRPC as well. The use of sequencing, combination therapy, somatic testing and precision medicine with PARP inhibitors will also be discussed. The course will also cover emerging second and third line therapies for CRPC as well as sequencing.

Learning Objective 1: Identify appropriate use of genetic testing, genetic counseling as well as somatic testing.

Learning Objective 2: Describe appropriate use of treatment-related to specific genetic alterations.

Learning Objective 3: Identify appropriate combination therapy with ADT plus novel androgen receptor pathway inhibitors and chemotherapy. Early treatment intensification as well as appropriate de intensification will be discussed in mHSCPC.

Learning Objective 4: Describe the treatments for non-metastatic CRPC and oncologic outcomes based on AUA/SUO and NCCN Guidelines.

Learning Objective 5: Counsel patients on available treatment options for CRPC as well as combination therapy and sequencing based on AUA/SUO and NCCN Guidelines.