AI and Supercomputing for Multi-Messenger Astrophysics: A Revolution in the Making

I this talk I describe how AI and supercomputing have transformed the landscape of multi-messenger astrophysics, touching every aspect of this multifaceted scientific endeavor, from multi-scale and multi-physics simulations to data-driven discovery. I will describe a blueprint to transform seminal ideas into physics-inspired, automated, AI-driven frameworks for scientific discovery at scale.