· What strategies can we use to identify the best combinations?
o Using immunology as a guide?
o Combinations of any active compound?
· What are the major mechanisms we need to focus on?
· How successful have targeted combinations been so far?
o IO-IO/ IO-Non-IO combos / Targeting the TME / Angiogenesis inhibitors / Standard of care agents
· What are the best biomarkers for combination studies?
· What major challenges remain?