Aldevron's CRISPR-Associated Nucleases for Gene Editing: Tools to Support Discovery and Therapeutic Programs

Aldevron's CRISPR-Associated Nucleases for Gene Editing: Tools to Support Discovery and Therapeutic Programs

Poster Zone

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Gene editing using CRISPR-associated nucleases, including SpCas9, offers a novel approach to treat many diseases. SpCas9 now is being evaluated in multiple preclinical and clinical programs. While many vendors offer research-grade SpCas9, these nucleases are not applicable to clinical trials due to construct design and quality grade. Aldevron offers SpCas9 and AsCpf1 nucleases optimized for development and clinical applications. In addition to wild-type SpCas9, Aldevron now offers SpyFi™ Cas9 which supports gene editing with significantly reduced offtarget effects. Aldevron's gene editing proteins are supported by a robust, scalable manufacturing protocol and an extensive quality package. These proteins are available in a range of quality grades from research grade to GMP, allowing for a seamless transition from research applications to the clinic. Poster is a narrated presentation with option to download full PDF version. View it here: https://youtu.be/gnQ4FXU5Tw4
AldevronLatest News: Aldevron Ranked Number 287 Fastest-Growing Company in North America on Deloitte’s 2020 Technology Fast 500™  Founded in 1998, Aldevron serves the biotechnology industry with custom production of nucleic acids, proteins, and antibodies. Thousands of clients worldwide rely on Aldevron-produced plasmid DNA, RNA, gene editing enzymes and more for biological research projects from discovery to clinical trials and commercial applications. These efforts help accelerate development of treatments for diseases such as cancer, infectious disease, pediatric disorders and rare diseases. Aldevron specializes in cGMP manufacturing and is known for inventing the GMP-Source® quality system. Our mission is to be a partner in the development of medicines that improve patients’ lives while serving clients, employees, and the community, while constantly looking for new and better ways to give researchers the products and services they need. Aldevron operates the largest cGMP plasmid DNA manufacturing facility in the world, located in Fargo, North Dakota, which serves as company headquarters, with additional production facilities in Madison, Wisconsin.  What can we do for you? Learn more about our products and services on our website  Watch our continuing growth as our campus expands!  Want to join the fastest growing biologics manufacturer in the region? Aldevron is hiring! 

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