Dielectric Spectroscopy as a PAT Tool for the Viral Vector Manufacturing Process.

Dielectric Spectroscopy as a PAT Tool for the Viral Vector Manufacturing Process.

Poster Zone Area
Dielectric Spectroscopy as a PAT Tool for the Viral Vector Manufacturing Process.
Dielectric Spectroscopy as a PAT Tool for the Viral Vector Manufacturing Process.

Information

Dielectric Spectroscopy is a technique which is commonly used as a process analytical tool to monitor and control cell growth and characteristics within biopharmaceutical manufacturing processes by determining the permittivity (capacitance per cm) of cell culture within a bioreactor. The application of this technology is utilised in both suspension and adherent cell cultures for viable cell counting and has demonstrated to have additional analytical benefits when applied to virus manufacturing processes. This tool has been shown to facilitate the increase of and reduced variation in batch productivity by providing real time, actionable feedback, helping to address industry issues surrounding meeting vector demand and batch-to-batch repeatability.
Link to Poster
https://chilp.it/49f2144
Aber Instruments Ltd Aber produces trusted GMP ready sensors for online, real-time viable cell biomass measurements. The standard dimension capacitance-based sensors are supplied globally for biopharma, biotech and industrial applications. The sensors can replace offline measurements facilitating sample-free online monitoring, PAT and automation. They are available in reusable and single-use formats and are scalable from mini-scale through to manufacturing. Aber's sensors have been used across many applications including cell and gene therapy and also within viral vector production. Expedite time-to-market and establish a robust, high yield bioprocess with Aber. 

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