An Integrated Workflow for the Analysis of Oligonucleotides and Their Impurities by Agilent High-Resolution LC/(Q-)Tof Mass Spectrometry

An Integrated Workflow for the Analysis of Oligonucleotides and Their Impurities by Agilent High-Resolution LC/(Q-)Tof Mass Spectrometry

Applications

Information

Separation of the final oligonucleotide product from its closest impurity is challenging, as these impurities are highly related to the full-length product. Agilent offers a broad portfolio of solutions for oligonucleotide analysis to achieve accuracy and optimize speed.
URL
https://www.agilent.com/cs/library/applications/an-oligonucleotide-impurity-analysis-advancebio-6545xt-bioconfirm-5994-4817en-agilent.pdf
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