Facilitating therapeutic antibody discovery with RenMab and RenLite humanized immunoglobulin mice.

Facilitating therapeutic antibody discovery with RenMab and RenLite humanized immunoglobulin mice.

Thursday, April 1, 2021 5:20 PM to 5:40 PM · 20 min. (Africa/Abidjan)
Antibodies
Bispecific & multispecifics
Presentation

Information

  • RenMab mice carry fully human heavy chain and kappa light chain repertoire. 
  • RenLite mice share a common light chain and enable an efficient bi-specific antibody discovery process. 
  • Both RenMab and RenLite mice are proven to generate highly specific hits with high affinity. 
  • Robust immune response of RenMab and RenLite mice are comparable to wild type mice. 
  • Specific target gene Knockout of RenMab and RenLite mice enables robust immune response against challenging targets. 
  • Antibody discovery service with Beacon single B cell cloning speeds up the whole discovery process dramatically.  

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