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Amplifying antibody diversity with single-cell screening and immune repertoire sequencing
Monday, March 29, 2021 3:00 PM to 3:20 PM · 20 min. (Africa/Abidjan)
Antibodies
Protein engineering
Presentation
Information
- High throughput single-cell screening is enabling the rapid generation of large, diverse antibody sequence datasets
- By combining immune repertoire sequencing with functionally validated single-cell data, we further expand antibody diversity accessible for lead identification Celium™, AbCellera's interactive software, interprets these complex datasets using dynamic visual networks to guide the selection of valuable antibodies
- This unparalleled ability to both generate and visualize highly curated large datasets dramatically expands the pool of potential therapeutic candidates
Christopher Williamson, Senior Research Scientist, Abcellera