Transforming Laboratory Spectroscopy in to Implementable PAT Solutions - Simplifying the Analysis Without Losing Data Integrity and Information

Moving spectroscopic technology from the laboratory to a manufacturing line, for example in Pharma, is typically a challenge that is grossly underestimated until the attempt is made. Raman and A-TEEM Fluorescence spectroscopy are information rich, powerful technologies capable of solving many manufacturing and QA/QC analysis challenges in Pharma. However, even something as relatively straightforward as Raman spectroscopy can take many years to be developed to meet the long list of User Requirements for a Pharma manufacturing environment analysis. For a technique like A-TEEM Fluorescence there are even more challenges to overcome due to the nature of the source and broad wavelengths applied. With both Raman and A-TEEM spectroscopy this means that unless there are no other simpler sensors available you should not even try to develop a solution using these techniques. In this talk we will illustrate with examples the journey from Lab to PAT and explain how simplification can help and is critical in making that journey a success.