Wearable Smart Mask for Continuous Exhaled Breath Condensate Collection and Real-Time Molecular Analysis

Recent respiratory outbreaks have emphasized the need for advanced monitoring tools. While current methods focus on physical signals, exhaled breath condensate (EBC) offers a wealth of molecular information that remains underutilized due to collection challenges and limited on-site analytical tools. In this talk, I will present a smart mask designed for continuous, real-time harvesting and analysis of EBC. This innovative device integrates microengineered structures and advanced cooling mechanisms, such as hydrogels and radiative materials, to lower the breath interface temperature and enable efficient EBC condensation. The collected liquid is autonomously transported through capillary-driven channels to an electrochemical sensor chamber, where biomarkers like nitrite—key indicators of respiratory conditions such as asthma and COPD—are detected with high sensitivity. The lightweight, compact design ensures user comfort without compromising performance, with results transmitted wirelessly for real-time health monitoring. This smart mask represents a breakthrough in wearable diagnostics, offering non-invasive, on-site monitoring for respiratory and metabolic disorders.