The Pittsburgh Analytical Chemistry Award was established to recognize a scientist’s significant contributions to the field of Analytical Chemistry including; introducing of a significant technique, theory or instrument or providing exceptional training or a fertile environment for progress in Analytical Chemistry. The Society for Analytical Chemists of Pittsburgh (SACP) and the Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon) are pleased to announce that Professor Neil Kelleher from Northwestern University has been named the recipient of the 2023 Pittsburgh Analytical Chemistry Award (PACA), which will be presented to him at a special Award Symposium at Pittcon 2023 in Philadelphia next March. Professor Kelleher is an internationally recognized scholar, leader, mentor, and teacher in modern proteomics and biological mass spectrometry, inventing powerful new methods to analyze and understand how human cells work at the molecular level. He has authored over 400 publications with more than 38,000 citations; he is listed as an inventor on 12 patents, and he has launched three successful entrepreneurial spin- offs. Professor Kelleher notably established and directs the National Resource for Translational and Developmental Proteomics at Northwestern University. Through his Center, he provides unique top-down proteoform characterization to researchers throughout the USA and the rest of the world. His work related to the human proteoform project, histone modifications, and The Consortium for Top-Down Proteomics drives many important research projects forward. Neil Kelleher’s amazing creativity, productivity, and influence have redefined the boundaries of what’s possible in modern proteomics and measurement science as they are applied to chemistry, biology, and clinical and translational research. He is most deserving of the 2023 Pittsburgh Analytical Chemistry Award.