Seizure Assessment and Forecasting with Efficient Rapid-EEG (SAFER) Trial

The SAFER study will inform physicians about the non-inferiority of a one-hour rapid-electroencephalogram (rrEEG) to a one-hour conventional-EEG (cEEG) for seizure forecasting using the 2HELPS2B score. There is currently an unmet need for EEG resources and a 2–11-hour delay from order to cEEG start. In this context, our results can improve in-patient care for patients at risk of seizures by reducing access time (to EEG), and for patients with non-convulsive seizures by reducing their time to diagnosis. In this work we inform the audience about the current trends in the use of rrEEG and cEEG at centers where these two systems are available. This may promote reflection on the rationale behind such trends. Altogether, this study provides evidence for discussion among clinicians and administrative staff to improve their neuromonitoring frameworks and practices. Our results were completed in the last three months. A regular submission was not possible due to prior commitments of the authors.