The Fraunhofer ITWM Competence Center for HPC presents innovative solutions based on the GASPI Programming Model and GPI-Space runtime that support our customers in the HPC, Big Data and Machine Learning industry. Workflow automation and large-scale Deep learning are key topics. The GPI ecosystem provides scalability to simulations and increases productivity by high level abstraction. We push efficiency at all levels: applications, middleware and hardware through tightly coupled hardware/software co-design.