Custom Monoclonal Antibody (mAb) Production

Custom Monoclonal Antibody (mAb) Production

Manufacturing

Information

In Vivo has more than 20 years of experience in the development, production and purification of monoclonal antibodies (mAB). We processed over 3,500 different hybridoma clones in our lab, generating antibodies of all kinds of species (rat, mouse, human, etc.) and subclasses (IgMs, IgGs). Using in-vitro production in our proprietary serum-free media, we assure cost-efficient processes with a protein yield up to 500 g through high cell density fermentation (>2 x 10^7 cells per ml). Quality guaranteed: Highest purity Aggregate-free Endotoxin-free (<1EU/mg) No traces of bovine IgGs Perfect batch-to-batch uniformity Depending on the productivity of your cell line and the desired amount of antibody, our prices vary between € 5 and € 55 per mg of purified mAB. We are ready for a test production to provide you with an individualized quote. Test production includes: Adaptation to our serum-free media Cultivation at 1-liter scale Purification with protein-A/G chromatography Yield guarantee of 10 mg of purified antibody Price: € 999.00 Customers ordering antibodies on a regular basis can take advantage of our Antibodies-On-Demand service.
InVivo BioTech Services GmbHInVivo is an ISO-certified German contract manufacturing organization (CMO) with more than 20 years of experience in cell culture and the development and production of monoclonal antibodies and recombinant proteins  for research, diagnostic and pre-clinical use. As an independent service provider, InVivo offers cost-effective outsourcing solutions plus a wide range of different expression systems to meet customer needs. We work with companies worldwide, including major diagnostic companies, research institutes and biopharmaceutical companies. We provide a complete range of antibody services, from antibody optimization and development to protein labelling. For monoclonal antibody production, our capacity ranges from  the milligram to the kilogram scale, and we have experience in the expression of antibodies from all kinds of subclasses and species. Besides mAB production, InVivo also focuses on the expression of recombinant proteins, including difficult-to-express proteins. Therefore we established a proprietary, highly-optimized expression system for transient gene expression in HEK cells, called InVest. This system combines an optimized host cell line, sophisticated vector design, large-scale plasmid preparation, serum-free cultivation media and a novel transfection reagent. InVivo now offers diverse SARS-CoV-2 Antigens in large-scale quantities, which are suitable for the development of highly sensitive IVD kits. Please visit our website for more information: https://www.invivo.de/cell-line-development/sars-cov-2-antigens/ For more details on our complete service portfolio please visit www.invivo.de

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