Always prescribe a spacer with an MDI
When prescribing a metered dose inhaler, don’t forget to include a AEROCHAMBER* brand of chambers for both children and adults. AEROCHAMBER* VHC is proven to deliver inhaler medication better than the inhaler alone.1,2,3,4
AEROCHAMBER* brand of chambers improve lung delivery by consistently delivering the intended dose, regardless of inhaler technique. A recent third-party pharmacokinetic study demonstrated that AEROCHAMBER PLUS* FLOW-VU* chamber optimizes lung delivery, even in healthy adults trained on correct technique.1
If using an MDI alone, even a short half second inhalation delay reduces the predicted lung delivery to approximately 1% of the intended dose. AEROCHAMBER* device holds the medication suspended for an extended period of time, allowing patients more time to inhale their medication.
When combined with an MDI, the AEROCHAMBER PLUS* FLOW-VU* chamber filters out the larger particles that would deposit in the back of the throat which could lead to side-effects such as hoarseness, sore throat, or thrush.5 Did you know that if using the MDI alone up to 10x as much medication can deposit in the back of the throat?5
1 Dorinsky P et al. Relative Bioavailability of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Administered With and Without a Spacer: Results of a Phase I, Randomized, Crossover Trial in Healthy Adults. Clin Ther. 42 (2020), 634-648.
2 Suggett J et al. The impact of inhalation delay on lung drug delivery: using functional respiratory imaging (FRI) to compare metered dose inhaler (MDI) and MDI/Valved Holding Chamber (VHC) Systems. Am J Respir Crit Care Med 2020;201:A5889.
3 Canadian Thoracic Society – 2010 Consensus Summary for children six years of age and over, and adults.
4 Global Strategy for Asthma Management and Prevention 2021 (Global Initiative on Asthma) (www.ginasthma.com)
5 Suggett J et al. Drug Delivery to the Lungs 28, Dec 2017.